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A bibliometric analysis of the scientific production of Center for Geophysical Research (CIGEFI) of the University of Costa Rica in scientific journals from 1979 to 2011
(2013-07-01)This scientific article presents an analysis about the work belonging to the Center for Geophysical Research (CIGEFI) of the University of Costa Rica since its inception in 1979 until 2011. It highlights the most productive ... -
A biocomputational platform for the automated construction of large-scale mathematical models of miRNA-transcription factor networks for studies on gene dosage compensation
(2016-11-09)Cancer complexity and resistance is mediated by cell-to-cell heterogeneity, which is the consequence of the enormous instability of its genetic material. It is unknown how cancer cells are able to withstand the effects ... -
A bright future for integrative venomics
(2015-10)Venomous secretions are produced by a myriad of animal species, from invertebrates to vertebrates. As a general rule, peptides and proteins represent the most abundant and functionally relevant components of these dangerous ... -
A Call for Incorporating Social Research in the Global Struggle against Snakebite
(2015-09-17)In Africa, Asia, Latin America, and parts of Oceania, envenoming after snakebite is a serious public health problem. Conservative data suggest that between 1.2 and 5.5 million people suffer snakebites every year, resulting ... -
A case-control study of breast cancer and hormonal contraception in Costa Rica
(1987)By 1981, 11% of married women in Costa Rica ages 20-49 years had used depot-medroxyprogesterone acetate (DMPA) and 58% had used oral contraceptives (OCs). Since 1977, the Costa Rican Ministry of Health has maintained a ... -
A catalytically-inactive snake venom Lys49 phospholipase A2 homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages
(2013-05-15)The effects of a snakevenom Lys-49phospholipaseA2 (PLA2) homolog named MT-II,devoid of enzymatic activity, on the biosynthesis of prostaglandins and protein expression of cyclooxygenase-2(COX-2) and signaling pathways ... -
A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C
(2005-07-22)Clostridium perfringens phospholipase C (Cp-PLC), also called alpha-toxin, is the major virulence factor in the pathogenesis of gas gangrene. Previously, a cellular UDP-Glc deficiency was related with a hypersensitivity ... -
A collaboration experience between EBCI and OTS: information as common denominator
(2015-01-01)This article systematizes the collaborative experience between two specialized institutions, such as the School of Library and Information Science (EBCI) at the University of Costa Rica (UCR) and the Organization for ...