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dc.creatorCuenca Berger, Patricia
dc.creatorRamírez Mayorga, Vanessa
dc.date.accessioned2015-03-02T18:08:39Z
dc.date.available2015-03-02T18:08:39Z
dc.date.issued2002-06
dc.identifier.citationhttp://revistas.ucr.ac.cr/index.php/rbt/article/view/16436
dc.identifier.issnISSN 0034-7744
dc.identifier.urihttp://hdl.handle.net/10669/11329
dc.descriptionArtículo científico -- Universidad de Costa Rica. Instituto de Investigaciones en Salud, 2002es_ES
dc.description.abstractPesticide use in Costa Rica is very high and all year round. A high percentage of what is sprayed remains in the environment and in the living organisms around. This situation brings contamination and health problems to people in contact with them. The onset of adverse effects may be in the short or the long term, and symptoms vary widely, from headaches to cancer. Much research in this area has been devoted to acute or chronic effects, and not until recently to the genotoxic effect of pesticides. This study evaluated the genotoxic effect of pesticides used in banana packing activities, using the comet assay (single cell electrophoresis) as the biological marker in lymphocytes. This was a case-control double blind study of 30 exposed women from 15 banana farms and 28 women not occupationally exposed to pesticides from the same geographic area. Results show damage to single stranded DNA after working from 5 to 15 years (R2=0.12). In Costa Rica we do not have an historical record of the kind of pesticides used in banana farms, the period of time and for how long were they used. This prevented further analysis concerning dose, frequency of exposure and use of new or old kind of pesticides in the farms in relation to DNA damage. The comet assay is of value in the genetic monitoring of pesticide exposed populationses_ES
dc.description.sponsorshipUniversidad de Costa Rica. Personal del INISA, a Arodys Robles por el apoyo estadístico y a Emilio Rojas por sus comentarios y sugerencias. Esta investigación fue financiada por la Vicerrectoría de Investigación de la Universidad de Costa Rica (proyecto N. 742-95-277), FUNDEVI, Organización Panamericana de la Salud a través del programa PLAGSALUD y el CONICIT.es_ES
dc.language.isoeses_ES
dc.publisherRevista de Biología Tropical 50 (2):507-518, 2002es_ES
dc.subjectSingle cell electrophoresises_ES
dc.subjectpesticideses_ES
dc.subjecthuman populations,es_ES
dc.subjectlymphocyteses_ES
dc.subjectbiomonitoringes_ES
dc.subjectCosta Ricaes_ES
dc.subjectbanana plantationses_ES
dc.subjectfemale farmers,es_ES
dc.subjectDNA.es_ES
dc.titleDaño del ADN en trabajadoras bananeras expuestas a plaguicidas en Limón, Costa Ricaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES
dc.identifier.codproyecto742-95-277


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