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El uso de animales de experimentación en la investigación biomédica en Costa Rica
Using Experimental Animal in Biomedical Research in Costa Rica
(Acta Médica Costarricense 52(3), 2010-07)
El progreso en la investigación médica y biológica ha dependido en gran medida del uso de animales
experimentales Dada la importancia que históricamente han tenido los animales como reactivos
biológicos en la investigación ...
Fragilidad osmótica de los eritrocitos de carnero en relación con su uso en el laboratorio clínico
(Revista Costarricense de Ciencias Médicas 14(1,2). 1993, 1993-03)
Al notar que los eritrocitos de carnero del Bioterio del Hospital San Juan de Dios, San José, Costa Rica, hemolizaban espontáneamente, fueron comparados, por medio de una serie de ensayos de fragilidad osmótica, con los ...
Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
(2016-03)
Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased
pathogenic potential of these strains has been attributed to several factors but is still ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
(2016-12-01)
Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and
medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite
the outbreaks ...
Immunohistochemical demonstration of the binding of bothrops asper myotoxin to skeletal muscle sarcolemma
(1987)
The binding of Bothrops asper myotoxin to mouse skeletal muscle was studied at both the light and electron microscope levels using the peroxidase anti-peroxidase technique. The toxin binds to muscle cell sarcolemma, and ...
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
(2009-12-01)
Envenomations by Bothrops asper are often associated with complex and severe local pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and hemorrhage. The pathogenesis of these alterations ...
Arboviral encephalitis in Costa Rican horses: 2009-2016
(2016-12)
Arbovirus of the genus Alphavirus and Flavivirus
can cause febrile illness and sometimes neurological disease
in both humans and animals. West Nile Virus (WNV), Eastern
Equine Encephalitis Virus (EEEV), Western Equine ...
The evolution of diarrhoeal diseases and malnutrition in Costa Rica: The role of interventions
(Assignment Child (61-62) p.195-224, 1983)
Costa Rica has an infant mortality rate of 17.7%, one of the lowest for developing countries. While it is noted that it is difficult to demonstrate the contributions of specific interventions in accounting for the drastic ...
The malnutrition-infection complex and its environment factors
(The Proceeding of the Nutrition Society 38(1):29-40. 1979, 1979-05)
Study of the genesis of malnutrition in contemporary traditional and transitional societies clearly reveals that malnutrition is a man-made condition or social disease. Apparently, malnutrition does not occur among wild ...