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dc.creatorAzofeifa Navas, Jorge
dc.creatorBarrantes Mesén, Ramiro
dc.creatorCremer, Marion
dc.date.accessioned2015-08-07T19:48:19Z
dc.date.available2015-08-07T19:48:19Z
dc.date.issued1995
dc.identifier.citationhttp://link.springer.com/journal/volumesAndIssues/439es_ES
dc.identifier.issn0340-6717
dc.identifier.issn1432-1203
dc.identifier.urihttp://hdl.handle.net/10669/15188
dc.descriptionArtículo científico -- Universidad de Costa Rica, Instituto de Investigaciones en Salud, 1995. A causa de las políticas de la revista en la que el artículo fue publicado no es posible distribuir la versión del editor/PDF.es_ES
dc.description.abstractA new 3.8-kb allele at the 5" region of the PGK 1 locus detected by the probe pSPT/PGK is reported. This variant was discovered in the Cabecar and Guaymi, two Chibchan Amerindian groups of Costa Rica. So far, a polymorphism that consists of an EcoRI/BglI (1.3-kb) variable site within an EcoRI/BglII (1.7-kb) fragment when DNA is simultaneously digested with EcoRI, BglI and BglII is known to occur in black and Caucasian populations. These two alleles were also found in the Amerindians tested. The newly described band is due to the lack of the BglII site situated 1.7 kb downstream from the EcoRI site and to the cleavage of another BglII site 2.1 kb downstream from the lacking one. This variant might be restricted to some Amerindian groups and perhaps also to Asiatic populations. Thus, it could be a useful marker in evolutive studies and for forensic applications. Moreover, the presence of a third allele in populations with Amerindian ancestry can increase the heterozygosity of the region disclosed by the pSPT/PGK probe, thus improving its application in issues dealing with X-chromosome activation ratios in femalees_ES
dc.description.sponsorshipUniversidad de Costa Rica, Instituto de Investigaciones en Saludes_ES
dc.language.isoen_USes_ES
dc.sourceHuman Genetics 96 (5): 626-627es_ES
dc.subjectpolimorfismoes_ES
dc.subjectPGKes_ES
dc.subjectgrupos amerindios chibchases_ES
dc.subjectCosta Ricaes_ES
dc.subjectHuman geneticses_ES
dc.subjectGenéticaes_ES
dc.titleLack of a BglII site at the 5’ region of the PGK 1 locus: a new variant discovered in two Chibchan Amerindian groups from Costa Ricaes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones en Salud (INISA)es_ES


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