• Hallazgos histopatológicos asociados a la presencia de arbovirus (chikungunya, zika, dengue, virus del nilo occidental) en murciélagos y aves silvestres en ambientes rurales domiciliares y peridomiciliares 

  Barrantes Murillo, Daniel Felipe (2020)

  Los arbovirus son virus transmitidos por vectores artrópodos. En Costa Rica, circulan algunos como el Dengue, Zika, Chikungunya y Nilo occidental. Los arbovirus poseen dos ciclos ecológicos diferentes para lograr mantenerse ...

• Efectos de la oxitetraciclina en un sistema de biopurificación: eliminación de triazinas y organofosforados y variación en la expresión de genes de degradación 

  Pérez Villanueva, Marta Eugenia (2020)

  La contaminación que provoca el mal uso de agroquímicos y el manejo inadecuado de sus desechos, puede afectar cuerpos de agua superficiales o subterráneos y grandes volúmenes de suelo. Los plaguicidas organofosforados y ...

• Guía para el estudio de la taxonomía y ecología de Myxomycetes 

  Lado Rodríguez, Carlos; Rojas Alvarado, Carlos Alonso (2020-06-17)

  Los Myxomycetes, también llamados hongos mucilaginosos plasmodiales, son un grupo de organismos eucariotas directamente relacionados con los Protozoos, por lo que también se les conoce como Mycetozoa. Están presentes ...

• Perfil epidemiológico y filogenético de Escherichia coli enteropatógena asociadas a gastroenteritis en pacientes pediátricos del Hospital Nacional de Niños “Dr. Carlos Sáenz Herrera”, enero 2015 a setiembre 2019 

  Mairena Acuña, Christopher (2020)

  Las enfermedades gastrointestinales son una de las principales causas de morbilidad y mortalidad en países en vías de desarrollo. Las infecciones causadas por los diversos patotipos de E. coli diarreogénicas tienen alta ...

• Determinación de la prevalencia del rasgo heterocigoto para hemoglobina S en las unidades de glóbulos rojos empacados utilizadas en el Hospital Nacional de Niños entre los meses de mayo y octubre del 2019 

  Campos Rodríguez, Diana (2020)

  La drepanocitosis es una enfermedad de relativa alta frecuencia en nuestro país y en el mundo en general, estos pacientes sufren de anemia hemolítica crónica y constantes complicaciones que requieren de frecuentes ...

• New Diet Quality Index of children and adolescents in Costa Rica 

  Núñez Rivas, Hilda Patricia; Holst Schumacher, Ileana; Campos Saborío, Natalia (2020)

  Introduction: There is an increasing interest in the study of indicators of the quality of the total diet through the study of food groups of certain dietary patterns. Objective: Analyze the diet of students of Costa Rica ...

• Exposure of dogs to Rickettsia spp. in Costa Rica: Risk factors for PCR-positive ectoparasites and seropositivity 

  Pacheco Solano, Katherine; Barrantes González, Alexander; Dolz, Gaby; Troyo Rodríguez, Adriana; Jiménez Rocha, Ana Eugenia; Romero Zúñiga, Juan José; Taylor Castillo, Mayra Lizeth (2019)

  Infection of dogs with Rickettsia spp. can result in inapparent, mild, or severe disease. Moreover, common dog ticks and fleas are able to transmit rickettsiae to nearby humans. In this study, the seroprevalence of spotted ...

• Resistencia de Aedes Aegypti (Diptera: Culicidae) a insecticidas organofosforados y piretroides en la localidad de Orotina, Alajuela, Costa Rica 

  Vargas Miranda, Karina; Troyo Rodríguez, Adriana; Calderón Arguedas, Ólger (2019)

  Objetivos: Determinar la resistencia de una cepa de Aedes. aegypti de Orotina a insecticidas organofosforados (temefós y malatión), y a piretroides (deltametrina, lambda cialotrina y cipermetrina). Métodos: La evaluación ...

• Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors 

  López Ureña, Diana; Orozco Aguilar, Josué; Chaves Madrigal, Yendry Pamela; Ramírez Mata, Andrea; Villalobos Jimenez, Amanda; Ost, Stefan; Quesada Gómez, Carlos; Rodríguez Sánchez, César; Papatheodorou, Panagiotis; Chaves Olarte, Esteban (2019)

  Clostridium difficile induces antibiotic-associated diarrhea due to the release of toxin A (TcdA) and toxin B (TcdB), the latter being its main virulence factor. The epidemic strain NAP1/027 has an increased virulence ...

• Brucella Genetic Variability in Wildlife Marine Mammals Populations Relates to Host Preference and Ocean Distribution 

  Suárez Esquivel, Marcela; Baker, Kate S.; Ruiz Villalobos, Nazareth; Hernández Mora, Gabriela; Barquero Calvo, Elías; Castillo Zeledón, Amanda; Jiménez Rojas, César; Chacón Díaz, Carlos; Cloeckaert, Axel; Chaves Olarte, Esteban; Thomson, Nicholas R.; Moreno Robles, Edgardo; Guzmán Verri, Caterina; González Barrientos, Rocío (2017)

  Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...

• The gut microbiome of the neotropical beetle Veturius sp. (coleoptera: passalidae): structure, composition and geneticpotential for cellulose degradation 

  Vargas Asensio, Juan Gabriel (2020)

  The global carbon cycle is responsible for maintaining the carbon dioxide and methane concentration in the atmosphere, influencing the weather and ocean acidification. Herbivores play an important role in the carbon cycle. ...

• Cimex lectularius Linnaeus, 1758 (Hemiptera: Cimicidae) in Costa Rica: First Case Report Confirmed by Molecular Methods in Central America 

  Cambronero Heinrichs, Juan Carlos; Sánchez Portilla, Laura Sofía; Calderón Arguedas, Ólger; Troyo Rodríguez, Adriana (2020)

  Cimex lectularius and Cimex hemipterus are the most common species of bedbugs that infest homes. Although case reports decreased substantially by the end of the 20th century, bed bugs, and especially C. lectularius, are ...

• Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): composition, biochemical activities and in vivo toxicity for potential prey 

  Díaz Oreiro, Cecilia; Rivera Hidalgo, Jennifer; Lomonte, Bruno; Bonilla Murillo, Fabián; Diego García, Elia; Camacho Umaña, Erika; Tytgat, Jan; Sasa Marín, Mahmood (2019)

  In this study, we characterize the venom of Centruroides edwardsii, one of the most abundant scorpions in urban and rural areas of Costa Rica, in terms of its biochemical constituents and their biological activities. C. ...

• Enzymatic labelling of venom phospholipase A2 toxins 

  Spolaore, Barbara; Fernández Ulate, Julián; Lomonte, Bruno; Massimino, Maria Lina; Tonello, Fiorella (2019)

  Almost all animal venoms contain secretory phospholipases A2 (PLA2s), 14 kDa disulfide-rich enzymes that hydrolyze membrane phospholipids at the sn-2 position, releasing lysophospholipids and fatty acids. These proteins, ...

• Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: phylogenetic relationships and characterization of Clarkitoxin-I-Mdum 

  Rey Suárez, Paola; Saldarriaga Córdoba, Mónica María; Torres Lamus, Uday Daniel; Marin Villa, Marcel; Lomonte, Bruno; Núñez Rangel, Vitelbina (2019)

  Micrurus mipartitus and M. dumerilii are the most medically important coral snakes in Colombia. Proteomic characterization of their venoms has previously shown that proteins of the three-finger toxin (3FTx) family ...

• A secreted phospholipase A2 induces formation of smooth muscle foam cells which trans-differentiate to macrophage-like state 

  Giannotti, Karina Cristina; Weinert, Sönke; Viana, Mariana Nascimento; Leiguez, Elbio; Araujo, Thaís L. S.; Laurindo, Francisco R. M.; Lomonte, Bruno; Braun Dullaeus, Rüdiger; Teixeira, Catarina de Fátima (2019)

  Vascular smooth muscle cells (VSMCs) loaded with lipid droplets (LDs) are markers of atherosclerosis. In this disease, inflammatory Group IIA-secreted phospholipase A2s (GIIA sPLA2s) are highly expressed in VSMCs, but ...

• Transfección mediante vehículos génicos basados enhidroxiapatita: eficacia y efectos sobre el tráfico intracelular 

  Chacón Arguedas, Carlos Daniel (2019)

  La hidroxiapatita (HAp), Ca10(PO4)6(OH)2, es un mineral miembro de las apatitas con una razón Ca/P de 1,67. Es el principal componente mineral de los huesos en los vertebrados y posee una serie de características de interés ...

• Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species 

  de la Rosa, Guillermo; Olvera, Felipe; Archundia, Irving G.; Lomonte, Bruno; Alagón Cano, Alejandro; Corzo, Gerardo (2019)

  Antivenoms are fundamental in the therapy for snakebites. In elapid venoms, there are toxins, e.g. short-chain α-neurotoxins, which are quite abundant, highly toxic, and consequently play a major role in envenomation ...

• Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants 

  Bustillo, Soledad; Fernández Ulate, Julián; Chaves Araya, Stephanie; Angulo Ugalde, Yamileth; Leiva, Laura C.; Lomonte, Bruno (2019)

  Bothrops diporus, previously considered a subspecies of the B. neuwiedi complex, is a medically relevant viperid in Northeastern Argentina. The venom of this species causes local tissue damage characterized by ...

• Three-finger toxins from the venom of Micrurus tschudii (desert coral snake): isolation and characterization of tschuditoxin-I 

  Lomonte, Bruno; Camacho Umaña, Erika; Fernández Ulate, Julián; Salas Arruz, María; Zavaleta Martínez Vargas, Alfonso (2019)

  Venoms from Micrurus (New World coral snakes) display potent peripheral neurotoxicity which may cause death by respiratory paralysis, yet many are poorly or not characterized. The major venom components of coral snakes are ...

View more