Microbiología
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Snakebite Envenomingin Latin America and the Caribbean
(2014)Envenomings induced by snakebites constitute a serious public health problem in Latin America. This condition affects predominantly vulnerable rural populations and has a high impact in regions where the provision of health ... -
Industrial Production and Quality Control of Snake Antivenoms
(2014)The production of snake antivenoms involves stages such as production of venom, immunization of animals to generate hyperimmune plasma, immunoglobulin purification, viral inactivation (or removal), and stabilization of the ... -
Resistencia a insecticidas en cepas de Aedes aegypti (Diptera: Culicidae) de tres distritos de la Región Pacífico Central de Costa Rica
(2018-12-30)Introducción: Aedes aegypti es vector de virus dengue, chikungunya y Zika en Costa Rica. Su alta incidencia y carencia de vacunas hacen del control vectorial, incluyendo el químico, la única alternativa para disminuir su ... -
Seasonal wetlands in the Pacific coast of Costa Rica and Nicaragua: environmental characterisation and conservation status
(2015)On the Pacific coast of Nicaragua and Costa Rica, rainfall patterns and clay-rich soils allow the development of extensive wetlands. These environments constitute unique habitats for the maintenance of aquatic biodiversity ... -
Multiple paths to aquatic specialisation in four species of Central American Anolis lizards
(2015-02-26)Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic ... -
Combustibles forestales superficiales y riesgo de incendio en dos estadios de sucesión secundaria y bosques primarios en el Parque Nacional Palo Verde, Costa Rica
(2015-06-22)Se cuantificó el combustible forestal superficial de los árboles en pie y del mantillo orgánico. También, se caracterizó la composición florística, en tres tratamientos de estadios sucesionales, de 10-25 años (29,88 ha) ... -
Membrane-damaging and cytotoxic sphingomyelinases and phospholipases
(2015-06-05)This chapter presents an overview of the classification, structure, and main physiopathological activities of bacterial sphingomyelinases and phospholipases, providing examples of their roles as virulence factors in several ... -
Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts
(2015-11-10)Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ... -
Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide
(2015-05-06)Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ... -
Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL)
(2015-08-29)Snake antivenoms are parenterally administered; therefore, endotoxin content must be strictly controlled. Following international indications to calculate endotoxin limits, it was determined that antivenom doses between ... -
Minipool Caprylic Acid Fractionation of Plasma Using Disposable Equipment: A Practical Method to Enhance Immunoglobulin Supply in Developing Countries
(2015-02-26)Plasma-derived immunoglobulin G (IgG) is on WHO’s Essential Medicines List, yet developing countries face severe shortages of this critical treatment. Infusion of IgG prepared from locally-collected plasma provides an ... -
Bacterial Sphingomyelinases and Phospholipases as Virulence Factors
(2016-06-15)Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of Gram-positive and Gram-negative bacteria. These enzymes hydrolyze ... -
Metaloproteinasas dependientes de Zinc: Protagonistas centrales en la Fisiopatología de Envenenamientos por Serpientes de la familia Viperidae
(2016)Se presenta y discute el papel que juegan las metaloproteinasas de los venenos de serpientes (SVMPs) de la familia Viperidae en la fisiopatología de los envenenamientos inducidos por mordeduras de estos reptiles. Se hace ... -
Desarrollo de la herpetocultura en Costa Rica: Situación actual de herpetarios y manejo ex situ de reptiles y anfibios
(2016-08-29)La tenencia de herpetofauna en cautiverio es una actividad que ha experimentado un enorme desarrollo en distintas partes del mundo, constituyéndose en la base de muchos programas de conservación, educación, e investigación. ... -
Hydrology Affects Environmental and Spatial Structuring of Microalgal Metacommunities in Tropical Pacific Coast Wetlands
(2016-02-22)The alternating climate between wet and dry periods has important effects on the hydrology and therefore on niche-based processes of water bodies in tropical areas. Additionally, assemblages of microorganism can show spatial ... -
A cryptic palm-pitviper species (Squamata: Viperidae: Bothriechis) from the Costa Rican highlands, with notes on the variation within B. nigroviridis
(2016-07-15)Middle America is one of the most biodiverse regions in the world, harboring an exceptional number of rare and endemic species. This is especially true of Middle American cloud forests, where montane specialists occupy ... -
Regional warming and the thermal regimes of American crocodile nests in the Tempisque Basin, Costa Rica
(2016-06-11)Spatial variation in global climate change makes population-specific responses to this enigmatic threat pertinent on a regional scale. Organisms with temperature-dependent sex determination (TSD) potentially possess a ... -
Methyltestosterone alters sex determination in the American alligator (Alligator mississippiensis)
(2016-07-09)Effects of xenobiotics can be organizational, permanently affecting anatomy during embryonic development, and/or activational, influencing transitory actions during adulthood. The organizational influence of endocrine-disrupting ... -
Improved biomass and protein production in solid-state cultures of an Aspergillus sojae strain harboring the Vitreoscilla hemoglobin
(2015-07-30)The biotechnological value of Aspergillus sojae ATCC 20235 (A. sojae) for production of pectinases in solidstate fermentation (SSF) has been demonstrated recently. However, a common drawback of fungal solid-state cultures ... -
CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity
(2014-10-07)The constant region of IgG antibodies mediates antiviral activities upon engaging host Fcγ receptors (FcγRs) expressed by a variety of immune cells, such as antibody-dependent cellullar cytotoxcity (ADCC) executed by natural ...
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