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Analysis of TcdB Proteins within the Hypervirulent Clade 2 Reveals an Impact of RhoA Glucosylation on Clostridium difficile Proinflammatory Activities
(2016-03)
Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased
pathogenic potential of these strains has been attributed to several factors but is still ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...
Molecular detection of Clostridium difficile on inert surfaces from a Costa Rican hospital during and after an outbreak
(2016-12-01)
Background: Hospital transmission of Clostridium difficile is fostered by contamination of surfaces and
medical equipment with spores highly resistant to disinfectants and regular cleaning procedures. Despite
the outbreaks ...
Immunohistochemical demonstration of the binding of bothrops asper myotoxin to skeletal muscle sarcolemma
(1987)
The binding of Bothrops asper myotoxin to mouse skeletal muscle was studied at both the light and electron microscope levels using the peroxidase anti-peroxidase technique. The toxin binds to muscle cell sarcolemma, and ...
Experimental pathology of local tissue damage induced by Bothrops asper snake venom
(2009-12-01)
Envenomations by Bothrops asper are often associated with complex and severe local pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and hemorrhage. The pathogenesis of these alterations ...
Arboviral encephalitis in Costa Rican horses: 2009-2016
(2016-12)
Arbovirus of the genus Alphavirus and Flavivirus
can cause febrile illness and sometimes neurological disease
in both humans and animals. West Nile Virus (WNV), Eastern
Equine Encephalitis Virus (EEEV), Western Equine ...
La construcción del ofidismo como problema científico-social en Costa Rica: una trayectoria histórica y relacional (1881-1988)
(Redes y estilos de investigación. Ciencia, Tecnología, Innovación y Sociedad en México y Costa Rica: 115-134, 2013)
El presente capítulo persigue el objetivo de analizar la construcción del ofidismo como problema científico-social en Costa Rica, entre 1881 y 1988, a partir del estudio del contexto, los actores y la institucionalización ...
Niveles de inmunoglobulinas séricas (IgG, IgA e IgM) en adultos jóvenes sanos, por el método de inmunodifusión radial
(1985)
Se determinó la concentración de IgG, IgA, e IgM en el suero de 49 estudiantes universitarios normales, de 18 a 25 años. Para esto se empleó el método de inmunodifusión radial, en placas comerciales. Los resultados fueron ...
Producción de placas de inmunodifusión radial para la cuantificación de IgG humana
(1985)
Se describe un método para la preparación de placas de inmunodifusión radial para la cuantificación de la lgG humana. El método se basó en las siguientes etapas: (1) aislamiento de lgG de suero normal
mediante cromatografía ...
Edema-forming activity of bushmaster (Lachesis muta stenophrys) and Central American rattlesnake (Crotalus durissus durissus) venoms and neutralization by a polyvalent antivenom
(1985)
The edema effect induced in mice by venoms of Crotalus durissus durissus and Lachesis muta stenophrys was studied . Minimum edema-forming doses were 11 and 5 ug, respectively . Edema developed very rapidly after injections ...