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Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas
(Bruno Lomonte. (2014). Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas. Cuba: RED BIOTOX-CYTED. pp.71-80, 2014)
Los péptidos sintéticos han ganado un lugar relevante dentro de la “caja de herramientas” de la investigación biomédica actual. Las técnicas de síntesis automatizada y el costo decreciente de los procesos, unidas a mejoras ...
Comparison between IgG and F(ab′)2 polyvalent antivenoms: neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions
(2001-06)
Whole IgG and F(ab′)2 equine-derived polyvalent (Crotalinae) antivenoms, prepared from the same batch of hyperimmune plasma, were compared in terms of neutralization of the lethal and defibrinating activities induced by ...
Cambios en el patrón electroforético del veneno de cascabela muda (Lachesis muta stenophrys) durante el almacenamiento bajo diferentes condiciones
(1985)
Liquid and lyophilized samples of Lachesis muta venom were stored at different temperatures and for different periods of time, and analyzed by polyacrylamide gel electrophoresis (PAGE) and immunoelectrophoresis. Only slight ...
Prevalencia de fasciolosis en bovinos de Costa Rica (2014). Comparación de cuatro técnicas diagnósticas
(2016)
Se realizó un estudio transversal con el objetivo de determinar la prevalencia de
fasciolosis en bovinos sacrificados en mataderos de Costa Rica y comparar cuatro técnicas
diagnósticas disponibles (inspección macroscópica ...
The need for an integrated approach in confronting snakebite envenoming in Latin America: the relevance of endogenous scientific and technological research
Hacia un abordaje integral del envenenamiento ofídico en América Latina: la importancia de la generación de conocimiento científico-tecnológico endógeno
(2016)
Snakebite envenomings constitute a serious public health problem on a global level, especially in Africa,
Asia and Latin America. In our Latin American region, it is estimated that at least 70,000 snakebite
cases occur ...
Arboviral encephalitis in Costa Rican horses: 2009-2016
(2016-12)
Arbovirus of the genus Alphavirus and Flavivirus
can cause febrile illness and sometimes neurological disease
in both humans and animals. West Nile Virus (WNV), Eastern
Equine Encephalitis Virus (EEEV), Western Equine ...
Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice
(1986-02)
The mode by which coral snake (Micrurus nigrocinctus) venom affects skeletal muscle was studied using a combined approach. The venom induced early functional and structural alterations in the plasma membrane of muscle ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...
Identification of cancer chemosensitivity by ODE and GMM modeling of heterogeneous cellular response to perturbations in fluorescent sphingolipid metabolism
(2016-11-11)
Cancer refers to a group of diseases in which cells display uncontrolled growth. Chemotherapy options are usually conditioned by generating resistance which is explained in part by the intrinsic heterogeneity of the ...
A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms
(Biochimica et Biophysica Acta - Proteins and Proteomics 1844(12):2265-2276, 2014-12)
Envenomation via snakebites is an important public health problem in many tropical and subtropical countries that, in addition to mortality, can result in permanent sequelae as a consequence of local tissue damage, which ...