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Mostrando ítems 1-20 de 1395

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    • A brief account of the history of family planning in Costa Rica 

      Carranza Maxera, María (2009)
      Costa Rica has been a focus of demographic attention for at least two reasons: its startling rate of natural population growth, which peaked at 3.8% during 1955 and 1960 and which was considered one of the highest in the ...
    • A case-control study of breast cancer and hormonal contraception in Costa Rica 

      Rosero Bixby, Luis; Grimaldo Vásquez, Carmen; Rovira, Elizabeth; Lee, Nancy C.; Oberle, Mark W.; Watley, Anne S. (1987)
      By 1981, 11% of married women in Costa Rica ages 20-49 years had used depot-medroxyprogesterone acetate (DMPA) and 58% had used oral contraceptives (OCs). Since 1977, the Costa Rican Ministry of Health has maintained a ...
    • A cross-national comparison of 12 biomarkers finds no universal biomarkers of aging among individuals aged 60 and older 

      Rehkopf, David H.; Rosero Bixby, Luis; Dow, William H. (2016)
      There is uncertainty about whether biological and anthropometric measures that are clinical risk factors for disease are universally associated with chronological age, or whether these correlations vary depending on the ...
    • A detailed analysis of open-field habituation and behavioral and neurochemical antidepressant-like effects in postweaning enriched rats 

      Brenes Sáenz, Juan Carlos; Padilla Mora, Michael; Fornaguera Trías, Jaime (2009-01-30)
      Our previous work has shown that male Sprague–Dawley rats reared in social isolation, standard housing and environmental enrichment differ in their spontaneous open-field activity and in some neurobehavioral depressive-like ...
    • A DNA pooling based system to detect Escherichia coli virulence factors in fecal and wastewater samples 

      Cortés Bratti, Ximena; Chacón Jiménez, Luz María; Taylor Castillo, Mayra Lizeth; Valiente Álvarez, Carmen Isabel; Alvarado Pérez, Irene (2012)
      The availability of a useful tool for simple and timely detection of the most important virulent varieties of Escherichia coli is indispensable. To this end, bacterial DNA pools which had previously been categorized were ...
    • A high performance liquid chromatography method with electrochemical detection of gamma-aminobutyric acid, glutamate and glutamine in rat brain homogenates 

      Monge Acuña, Andrea A.; Fornaguera Trías, Jaime (2009)
      Determination of γ-aminobutyric acid (GABA), glutamate (Glu) and glutamine (Gln) in animal models has been important to understand the normal function and clinical aspects of some neurological diseases. Quantification of ...
    • A new look at the determinants of nonnumeric response to desired family size: the case of Costa Rica 

      Riley, Ann P.; Hermalin, Albert I.; Rosero Bixby, Luis (1993)
      High levels of nonresponse or inappropriate response to items are a persistent concern in survey research because those who do not answer may not be representative of the study population. Thus nonresponse introduces ...
    • A novel myosin heavy chain gene in human chromosome 19q13.3 

      Leal Esquivel, Alejandro; Endele, Sabine; Stengel, Corinna; Huehe, Kartrin; Loetterle, Joachim; Barrantes Mesén, Ramiro; Winterpacht, Andreas; Rautenstrauss, Bernd (Gene: 312 p. 165-171, 2003-07)
      A human myosin heavy chain gene was identified in chromosome 19q13 by computational sequence analysis, RT-PCR and DNA sequencing of the cDNA. The complete cDNA has a length of 6786 bp and comprises 41 exons (40 coding) ...
    • A polymorphism in the MSH3 mismatch repair gene is associated with the levels of somatic instability of the expanded CTG repeat in the blood DNA of myotonic dystrophy type 1 patients 

      Morales Montero, Fernando; Vásquez Cerdas, Melissa; Santamaría Ulloa, Carolina; Cuenca Berger, Patricia; Corrales Acuña, Eyleen Vanessa; Monckton, Darren G. (2016-04)
      Somatic mosaicism of the expanded CTG repeat in myotonic dystrophy type 1 is age-dependent, tissuespecific and expansion-biased, contributing toward the tissue-specificity and progressive nature of the symptoms. Previously, ...
    • A Population-based Serosurveillance of Syphilis in Costa Rica 

      Larsen, Sandra A.; Oberle, Mark W.; Sánchez Braverman, Juana M.; Rosero Bixby, Luis; Vetter, Kathleen M. (1991-04)
      As part of a case-control study to investigate the high incidence of cervical cancer in Costa Rican women, the seroprevalence of the treponematoses, in particular, syphilis was determined. In each age group, women with a ...
    • A Protocol to Perform Systemic Lipopolysacharide (LPS) Challenge in Rats 

      Ramírez Chan, Karol Gabriela; Quesada Yamasaki, Daniel; Fornaguera Trías, Jaime (2019-01-01)
      Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria. In animals, intraperitoneal administration of LPS, stimulates innate immunity and the production of ...
    • A public health approach to the “Food-Malnutrition-Economic Recession” complex 

      Mata Jiménez, Leonardo (1988)
      The authors in this volume disagree as to whether the current economic world recession and its accompanying adjustment policies affect nutrition and health. Based on the data presented throughout this volume and the ...
    • A review of Bioinformatics training applied to research in Molecular Medicine, Agriculture and Biodiversity in Costa Rica and Central America 

      Orozco Solano, Allan; Morera Huertas, Jessica; Jiménez, Sergio; Boza Cordero, Ricardo (Briefings in Bioinformatics, 14(5): 661-670, 2013-04-13)
      Today, Bioinformatics has become a scientific discipline with great relevance for the Molecular Biosciences and for the Omics sciences in general. Although developed countries have progressed with large strides in ...
    • A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study 

      Escamilla, Michael; Hare, Elizabeth; Dassori, Albana; Peralta, Juan Manuel; Ontiveros, Humberto; Nicolini Sánchez, José Humberto; Medina, Rolando; Mendoza Rodríguez, Ricardo; Muñoz, Rodrigo; Almasy, Laura; Raventós Vorst, Henriette; Jerez, Álvaro (Am J Psychiatry 2009;166:442-449, 2009-02-02)
      The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
    • A Second Locus for an Axonal Form of Autosomal Recessive Charcot-Marie-Tooth Disease Maps to Chromosome 19q13.3 

      Leal Esquivel, Alejandro; Morera Brenes, Bernal; del Valle Carazo, Gerardo; Heuss, Dieter; Kayser, Corinna; Berghoff, Martin; Villegas Palma, Ramón; Hernández, Erick; Méndez, María; Hennies, Hans Christian; Bernhard, Neundörfer; Barrantes Mesén, Ramiro; Reis, André; Rautenstrauss, Bernd (American Journal Human Genetic ; 68 (1 p. 269-274, 2001)
      Autosomal recessive Charcot-Marie-Tooth disease (CMT) represents a heterogeneous group of disorders affecting the peripheral nervous system. The axonal form of the disease is designated as "CMT type 2" (CMT2), and one locus ...
    • A somatic coliphage threshold approach to improve the management of activated sludge wastewater treatment plant effluents in resource-limited regions 

      Chacón Jiménez, Luz María; Barrantes Jiménez, Kenia; Santamaría Ulloa, Carolina; Solano Barquero, Melissa; Reyes Lizano, Liliana; Taylor Castillo, Lizeth; Valiente Álvarez, Carmen Isabel; Symonds, ‪Erin Michelle; Achí Araya, María Rosario (2020-06)
      Effective wastewater management is crucial to ensure the safety of water reuse projects and 29 effluent discharge into surface waters. Multiple studies have demonstrated that municipal 30 wastewater treatment with ...
    • A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries 

      Schwarting, Rainer K. W.; Goldenberg, R.; Steiner, Heinz; Fornaguera Trías, Jaime; Huston, Joseph P. (1993)
      A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
    • Abdominal angiostrongylosis 

      Morera Villalobos, Pedro (1995)
      Abdominal angiostrongylosis, caused by Atigiostrongylus costaricensis (Morera and Cespedes, 1971) or Morerastrongylus rostaricensis (Chabaud, 1972), is a parasitic disease characterized by a granulomatous inflammatory ...
    • Abdominal obesity and hyperglycemia mask the effect of a common APOC3 haplotype on the risk of myocardial infarction 

      Ruiz Narváez, Edward A.; Sacks, Frank M.; Campos Núñez, Hannia (2008)
      Background: Plasma apolipoprotein (apo) C-III strongly predicts myocardial infarction (MI) and directly activates atherogenic processes in vascular cells. Genetic variation in the insulin response element of the APOC3 ...
    • Aberraciones cromosómicas en trabajadoras expuestas a plaguicidas 

      Cuenca Berger, Patricia; Ramírez Mayorga, Vanessa (Revista de Biología Tropical 52(3) p.623-628, 2004-12-15)
      The purpose of this work was to determine if the occupational exposure to those pesticides used at banana plantations’ packaging plants produces genetic damage to somatic cells of female workers. Chromosomal aberrations ...

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