Now showing items 1-10 of 36
Individual differences in the immobility behavior in juvenile and adult rats are associated with monoaminergic neurotransmission and with the expression of corticotropin-releasing factor receptor 1 in the nucleus accumbens
(Behavioural Brain Research, Vol. 252. pp. 77-87, 2013)
The study of individual differences provides an important methodological approach to analyze the neurobehavioral spectrum of a given cohort in order to understand brain function and disease. Based on immobility time in ...
Automated Video-Image Analysis of Behavioral Asymmetries
The analysis of behavioral asymmetries is a widely employed approach to investigate behavior in relation to functions of the brain. Out of the repertory of presently available measures, turning behavior is probably the one ...
A detailed analysis of open-field habituation and behavioral and neurochemical antidepressant-like effects in postweaning enriched rats
Our previous work has shown that male Sprague–Dawley rats reared in social isolation, standard housing and environmental enrichment differ in their spontaneous open-field activity and in some neurobehavioral depressive-like ...
The effect of chronic fluoxetine on social isolation-induced changes on sucrose consumption, immobility behavior, and on serotonin and dopamine function in hippocampus and ventral striatum
This study examined the effect of fluoxetine, a selective serotonin (5-HT) reuptake inhibitor, on isolation-induced changes on sucrose consumption and preference, spontaneous open-field activity, forced swimming behavior, ...
A high performance liquid chromatography method with electrochemical detection of gamma-aminobutyric acid, glutamate and glutamine in rat brain homogenates
Determination of γ-aminobutyric acid (GABA), glutamate (Glu) and glutamine (Gln) in animal models has been important to understand the normal function and clinical aspects of some neurological diseases. Quantification of ...
Behavioral asymmetries and recovery in rats with different degrees of unilateral striatal dopamine depletion
A detailed behavioral analysis during the first postoperative week was performed in rats which had sustained various degrees of unilateral neostriatal dopamine (DA) lesions by administration of the neurotoxin 6-hydroxydopamine ...
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries
A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Behavioral indices of moderate nigrostriatal 6–hydroxydopamine lesion: a preclinical Parkinson's model.
Asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6-hydroxydopamine into the substantia nigra. Animals with severe lesions, ...