Now showing items 1-9 of 9
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry
Although aging and environmental stimulation are well-known to affect cognitive abilities, the question of whether aging effects can be distinguished in already-mature adult rats has not been fully addressed. In the ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Prediction of Peak Aerobic Power among Costa Rican Older Adults
Introduction: The peak oxygen uptake (VO2peak) is considered a valid indicator of the cardiovascular system function, and when measured on a metabolic cart it is considered the gold standard for cardiorespiratory fitness. ...
Amerindian ancestry and extended longevity in Nicoya, Costa Rica
Objectives: The aim of this study was to address the hypothesis that Amerindian ancestry is associated with extended longevity in the admixed population of Nicoya, Costa Rica. The Nicoya Peninsula of Costa Rica has been ...
Measuring Socioeconomic Position From The Social Inequalities In Health Perspective?: The Case of Costa Rica
¿Cómo medir la posición socioeconómica en el marco de las inequidades sociales de salud?: El caso de Costa Rica
Introduction: Measuring socioeconomic position (SEP) is central in the analysis of social inequalities in health (SIH). It requires the use of updated instruments, adapted to a particular conceptual framework, taking into ...
Social inequalities in cancer survival: A population-based study using the Costa Rican Cancer Registry
Social inequalities in survival after cancer diagnosis have been described in several high-income countries, all cancer sites combined and for several specific cancer sites. The objective of this study was to analyze 5-year ...
Socioeconomic inequalities in cancer mortality: Is Costa Rica an exception to the rule?
Socioeconomic inequalities in cancer mortality have been described for a range of cancers sites worldwide, using diverse measures of socioeconomic position (SEP). These studies have shown a negative social gradient where ...
Behavioural characterisation of chronic unpredictable stress based on ethologically relevant paradigms in rats
The chronic unpredictable stress (CUS) paradigm is extensively used in preclinical research. However, CUS exhibits translational inconsistencies, some of them resulting from the use of adult rodents, despite the evidence ...
Distribución espacial de la enfermedad Charcot-Marie-Tooth en Costa Rica, 1990-2003
Spatial Distribution of the Charcot-Marie-Tooth Disease in Costa Rica,1990-2003
Objetivo: Evaluar la distribución espacial como indicador de la incidencia de la enfermedad de Charcot-Marie-Tooth por los egresos hospitalarios reportados en Costa Rica entre el período 1990-2003. Métodos: Se aplicó un ...