Search
Now showing items 1-10 of 34
The serotonin transporter 5-HTTPR polymorphism is associated with current and lifetime depression in persons with chronic psychotic disorders
(Acta Psychiatr Scand 2009: 119: 117–127, 2009-01-11)
Objective: Variation in the serotonin transporter gene (SLC6A4)
promoter region has been shown to influence depression in persons
who have been exposed to a number of stressful life events.
Method: We evaluated whether ...
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
(Human Biology Open Access Pre-Prints. Paper 34., 2013-10-09)
Study for the first time a random sample from all regions of the country with AIMS (Ancestry Informative Markers) to address the individual and regional admixture proportions. A sample of 160 male individuals was screened ...
Diagnosis of Schizophrenia in Latino Populations. A Comparison of Direct Interview and Consensus Based Multi-Source Methods
(Journal of Nervous and Mental Disease 2009;197: 530–535, 2009-07)
We determined the rates of agreement between diagnoses, using
the Diagnostic Interview for Genetic Studies (DIGS) and diagnoses arrived
at, using additional sources of information, to establish whether there are
differences ...
Caracterización de un grupo de pacientes con esquizofrenia en el Valle Central de Costa Rica
(AMC, vol 50 (3), julio-setiembre 2008, 2008)
La esquizofrenia es una enfermedad crónica con importantes
repercusiones sociales que afecta al 1% de la población mundial. Se describe las características de la esquizofrenia en una muestra de pacientes del Valle Central ...
High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees
(American Journal of Physical Anthropology 2012 July ; 148(3): 327–333., 2012-07)
Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial
DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming
that molecular evolution is clock-like) ...
Foro sobre salud mental 2011, conclusiones y pasos futuros
(Acta médica costarricense Vol 55 (3), julio-setiembre 2013, 132-138, 2013-07)
Antecedentes: la salud es un proceso social que tiene como fin el bienestar físico y mental del
individuo a través de todas las etapas de su vida. A pesar de numerosos esfuerzos, en Costa Rica, el
abordaje en salud mental ...
Genética de la esquizofrenia: avances en el estudio de genes candidatos
(Rev. biol. trop v.52 n.3, p. 467-473 sep. 2004, 2004)
Genetics of Schizophrenia: advances in the study of candidate genes. Schizophrenia is one of the
most severe mental disorders that affect 1% of the population worldwide. It is clear that both genetic and
environmental ...
Resultados de la categorización de una muestra de pacientes con diagnóstico de egreso de esquizofrenia
(Acta Médica Costarricense, abril-junio 2002, vol 44 (2), 2002-04)
La esquizofrenia es una enfermedad que afecta aproximadamente al 1% de la población mundial. Es
una de las enfermedades psiquiátricas más debilitantes con un alto costo económico, social, familiar y personal.
En Costa ...
Heritability of Cognitive Functions in Families of Successful Cognitive Aging Probands from the Central Valley of Costa Rica
(J Alzheimers Dis. 2011 ; 27(4): 897–907. doi:10.3233/JAD-2011-110782., 2011)
We sought to identify cognitive phenotypes for family/genetic studies of successful cognitive
aging (SCA; maintaining intact cognitive functioning while living to late old age).We
administered a battery of neuropsychological ...
In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation
(J Mol Med (Berl). 2010 November ; 88(11): 1133–1141, 2010-11)
Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune ...