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A schizophrenia gene locus on chromosome 17q21 in a new set of families of mexican and central american ancestry: evidence from the NIMH genetics of schizophrenia in latino populations study 

Escamilla, Michael; Hare, Elizabeth; Dassori, Albana; Peralta, Juan Manuel; Ontiveros, Humberto; Nicolini Sánchez, José Humberto; Medina, Rolando; Mendoza Rodríguez, Ricardo; Muñoz, Rodrigo; Almasy, Laura; Raventós Vorst, Henriette; Jerez, Álvaro (Am J Psychiatry 2009;166:442-449, 2009-02-02)
The present study investigated a new set of families of Latin American ancestry in order to detect the location of genes predisposing to schizophrenia and related psychotic disorders. Method: A genome-wide scan was performed ...
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Adjudicating Neurocognitive Endophenotypes for Schizophrenia 

Burk, Gary; Estrada, Jose; Peralta, Juan Manuel; Meyenberg, Naxhielli; Barrett, Jennifer; Nicolini Sánchez, José Humberto; Escamilla, Michael; Glahn, David C.; Almasy, Laura; Blangero, John; Pereira Castro, Mariana; Raventós Vorst, Henriette (American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 144B:242–249 (2007), 2007-03-05)
Although genetic influences on schizophrenia are well established, localization of the genes responsible for this illness has proven extremely difficult. Given evidence that genes predisposing to schizophrenia may be ...
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Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations 

Zavala, Juan Manuel; Dassori, Albana; Escamilla, Michael; Raventós Vorst, Henriette; Nicolini Sánchez, José Humberto; Ontiveros Sánchez de la Barquera, Jose Alfonso; Jerez, Álvaro; Contreras Rojas, Javier; Ramírez, Mercedes; Contreras, Salvador; Flores, Deborah; Leach, Robin J.; Armas, Regina; González, S. D. (Translational Psychiatry (2013) 3, e265, 2013-05-28)
Some of the most consistent findings have been in variants located in the ANK3 (ankyrin-G) gene located on chromosome 10q. Schultz et al.4 found that BP risk alleles in ANK3, rs9804190 and rs10994336, contributed ...
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Caracterización de un grupo de pacientes con esquizofrenia en el Valle Central de Costa Rica 

Montero Vega, Ana Patricia; Dassori, Albana; Escamilla, Michael; Raventós Vorst, Henriette; Contreras Rojas, Javier (AMC, vol 50 (3), julio-setiembre 2008, 2008)
La esquizofrenia es una enfermedad crónica con importantes repercusiones sociales que afecta al 1% de la población mundial. Se describe las características de la esquizofrenia en una muestra de pacientes del Valle Central ...
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The epsin 4 gene is associated with psychotic disorders in families of Latin American origin 

Escamilla, Michael; Dae Lee, Byung; Ontiveros Sánchez de la Barquera, Jose Alfonso; Nicolini Sánchez, José Humberto; Mendoza Rodríguez, Ricardo; Muñoz, Rodrigo; Medina, Rolando; Walss Bass, Consuelo; Armas, Regina; Contreras, Salvador; Dassori, Albana; Raventós Vorst, Henriette; Jerez, Álvaro; Figueroa, Andrés; Ramírez, Mercedes (Schizophrenia Research vol. 106, num 2 (2008) 253–257, 2008-10-20)
This study attempted to replicate evidence for association of the Epsin 4 gene (which encodes enthoprotin, a protein involved in vesicular transport) to schizophrenia in a new sample of families segregating schizophrenia ...
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Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences 

Silva de la Fuente, Sandra Maria; Escamilla, Michael; Ontiveros, Humberto; Mendoza Rodríguez, Ricardo; Muñoz, Rodrigo; Raventós Vorst, Henriette; Campos Sánchez, Rebeca; Barrantes Mesén, Ramiro (Human Biology, October 2006, v. 78, no. 5, pp. 551–563., 2006)
Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to ...
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Cefalea en racimos 

Van Vliet, J. A.; Ferrani, M. D.; Peralta, Juan Manuel; Raventós Vorst, Henriette; Chaves Sell, Franz (Acta Médica Costarricense, Julio-Setiembre 2003, vol 45 (3) 97-101, 2003)
La cefalea en racimos (CR) o “neuralgia de Horton”, es un tipo relativamente raro de cefalea que se presenta en forma de ataques y cuya severidad le ha dado el nombre de “dolor de cabeza suicida”. Debido a que la CR es una ...
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High mitochondrial mutation rates estimated from deep-rooting Costa Rican pedigrees 

Castri, Loredana; Barrantes Mesén, Ramiro; Pereira Reyes, Reinaldo; Luiselli, Donata; Pettener, Davide; Barbujani, Guido; Madrigal, Lorena; Meléndez Obando, Mauricio O.; Villegas Palma, Ramón; Raventós Vorst, Henriette (American Journal of Physical Anthropology 2012 July ; 148(3): 327–333., 2012-07)
Estimates of mutation rates for the noncoding hypervariable Region I (HVR-I) of mitochondrial DNA (mtDNA) vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock-like) ...
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Heritability of Cognitive Functions in Families of Successful Cognitive Aging Probands from the Central Valley of Costa Rica 

Greenwood, Tiffany A.; Beeri, Michal S.; Schmeidler, James; Valerio Aguilar, Daniel; Raventós Vorst, Henriette; Mora Villalobos, Lara; Camacho, Karla; Carrión Baralt, José R.; Angelo, Gary; Almasy, Laura; Sano, Mary; Silverman, Jeremy M. (J Alzheimers Dis. 2011 ; 27(4): 897–907. doi:10.3233/JAD-2011-110782., 2011)
We sought to identify cognitive phenotypes for family/genetic studies of successful cognitive aging (SCA; maintaining intact cognitive functioning while living to late old age).We administered a battery of neuropsychological ...
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In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation 

Marballi, Ketan; Quiñones, Marlon; Jiménez, Fabio; Escamilla, Michael; Raventós Vorst, Henriette; Soto Bernardini, María Clara; Ahuja, Seema S.; Walss Bass, Consuelo (J Mol Med (Berl). 2010 November ; 88(11): 1133–1141, 2010-11)
Neuregulin 1 (NRG1) has been implicated in several disorders including breast cancer, multiple sclerosis, and schizophrenia. Also, recent evidence suggests that NRG1 may play a role in regulation of inflammation and immune ...
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