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Behavioral asymmetries and recovery in rats with different degrees of unilateral striatal dopamine depletion
A detailed behavioral analysis during the first postoperative week was performed in rats which had sustained various degrees of unilateral neostriatal dopamine (DA) lesions by administration of the neurotoxin 6-hydroxydopamine ...
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries
A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
Behavioral indices of moderate nigrostriatal 6–hydroxydopamine lesion: a preclinical Parkinson's model.
Asymmetries in turning and scanning were investigated in rats with different degrees of neostriatal dopamine depletion after unilateral injections of 6-hydroxydopamine into the substantia nigra. Animals with severe lesions, ...
Early behavioral changes after nigro-striatal system damage can serve as predictors of striatal dopamine depletion
1. Rats which had received a unilateral injection of 6-OHDA into the substantia nigra were assigned to four lesion groups according to the degree of DA depletion in the neostriatum. In these animals, behavioral changes in ...
Automated Video-Image Analysis of Behavioral Asymmetries
The analysis of behavioral asymmetries is a widely employed approach to investigate behavior in relation to functions of the brain. Out of the repertory of presently available measures, turning behavior is probably the one ...
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...