Now showing items 1-10 of 36
Individual differences in the forced swimming test and neurochemical kinetics in the rat brain
(Physiology & Behavior 126(1):60-69, 2014-02-08)
Individual differences in the forced swimming test (FST) could be associatedwith differential temporal dynamics of gene expression and neurotransmitter activity. We tested juvenile male rats in the FST and classified ...
Un método simple para la recolección, extracción y medición de catecolaminas en orina de adultos mayores
A simple method to collect, extract and measure urinary catecholamines in elderly people
La medición de catecolaminas en orina ha sido utilizada tanto para diagnóstico como para la investigación. Este trabajo propone algunas modificaciones y condiciones estandarizadas para llevar a cabo la recolección ...
Analogía computacional del cerebro y la mente
En los últimos dos siglos se ha dado un especial interés por desentrañar los misterios que rodean a la mente y al cerebro. Es más, esta separación ha hecho suponer que la mente es una cuestión de orden espiritual y que ...
Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats
Developmental and social factors are known to play a crucial role in the pathogenesis of affective disorders. Although it has been demonstrated that early life aversive experiences can be a risk factor in the development ...
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...
Effects of environmental enrichment and social isolation on sucrose consumption and preference: Associations with depressive-like behavior and ventral striatum dopamine
Little attention has been directed towards environmental control of sensitivity to natural reward and its possible relationship with other motivated behaviors, besides the well-known effects of environmental enrichment and ...
Association of Apolipoprotein E-e4 and Dementia Declines with Age
To study the association of dementia with apolipoprotein E-e4 (APOE-e4) and its interaction with age in a nonagenarian Costa Rican group (N-sample) and a general elderly contrast group (GE-sample). In both case-control ...
Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
Dawley rats were reared from weaning in either social isolation, standard laboratory conditions, or environmental enrichment. Open-field activity was assessed at postnatal days 37, 65, 93 and 107 and 1 h before the last ...
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry
Although aging and environmental stimulation are well-known to affect cognitive abilities, the question of whether aging effects can be distinguished in already-mature adult rats has not been fully addressed. In the ...