Now showing items 1-10 of 36
Time course of deficits in open field behavior after unilateral neostriatal 6-hydroxydopamine lesions
In this study, the degree and time course of deficits in open field behavior was analyzed in male Wistar rats (aged 1 year) which had received unilateral neostriatal lesions with 6-OHDA. The post-mortem neurochemical ...
Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum
Dawley rats were reared from weaning in either social isolation, standard laboratory conditions, or environmental enrichment. Open-field activity was assessed at postnatal days 37, 65, 93 and 107 and 1 h before the last ...
Un método simple para la recolección, extracción y medición de catecolaminas en orina de adultos mayores
A simple method to collect, extract and measure urinary catecholamines in elderly people
La medición de catecolaminas en orina ha sido utilizada tanto para diagnóstico como para la investigación. Este trabajo propone algunas modificaciones y condiciones estandarizadas para llevar a cabo la recolección ...
Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats
Developmental and social factors are known to play a crucial role in the pathogenesis of affective disorders. Although it has been demonstrated that early life aversive experiences can be a risk factor in the development ...
Effects of environmental enrichment and social isolation on sucrose consumption and preference: Associations with depressive-like behavior and ventral striatum dopamine
Little attention has been directed towards environmental control of sensitivity to natural reward and its possible relationship with other motivated behaviors, besides the well-known effects of environmental enrichment and ...
Neurociencias y Psicologíaen Costa Rica: Programa de Investigación en Neurociencias
Neuroscience and Psychology in Costa Rica: Neuroscience Research Program
El presente artículo es una reseña histórica del Programa de Investigación en Neurociencias(PIN) de la Universidad de Costa Rica, que fue creado en el año 1999. Actualmente,está organizado en tres áreas de investigación: ...
Behavioral and neurochemical characterization of maternal care effects on juvenile Sprague–Dawley rats
Maternal care represents a major constituent of early life environment and has the potential to modulate critical neurobehavioral responses to stress. The aim of the present study was to determine the effects of naturally ...
A video image analyzing system for open-field behavior in the rat focusing on behavioral asymmetries
A video image analyzing system is presented which measures turning behavior, thigmotactic scanning and locomotion in rats. The system works by analyzing digitized video images obtained by a black/white video camera. Turning ...
Sub-chronic administration of St. John’s wort reverses anxiety- and depressive-like behaviors induced by two different protocols of chronic stress
La administración sub-crónica de hierba de San Juan revierte las conductas de ansiedad y depresión inducidas por dos protocolos distintos de estrés crónico
Introduction. St. John’s wort (Hypericum perforatum, HP) is one of the most used herbal medicines. Here we investigated the putative antidepressive- and anxiolytic-like effects of HP, by using a well-validated rat model ...
Early behavioral changes after nigro-striatal system damage can serve as predictors of striatal dopamine depletion
1. Rats which had received a unilateral injection of 6-OHDA into the substantia nigra were assigned to four lesion groups according to the degree of DA depletion in the neostriatum. In these animals, behavioral changes in ...