Browsing Biología by Subject "uPAR"

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Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis

Alpízar Alpízar, Warner; Skindersoe, Mette Elena; Rasmussen, Lone; Kriegbaum, Mette Camila; Christensen, Ib J.; Lund, Ida Katrine; Illemann, Martin; Laerum, Ole Didrik; Krogfelt, Karen Angeliki; Andersen, Leif Percival; Ploug, Michael (2020)

(1) Background: Persistent Helicobacter pylori infection is the most important risk factor for gastric cancer. The urokinase receptor (uPAR) is upregulated in lesions harboring cancer invasion and inflammation. Circumstantial ...
Inflammation and uPAR-Expression in Colorectal Liver Metastases in Relation to Growth Pattern and Neo-adjuvant Therapy

Eefsen, Rikke Loevendahl; Engelholm, L.; Alpízar Alpízar, Warner; Van den Eynden, Gert G. E.; Vermeulen, Peter B.; Christensen, Ib J.; Laerum, Ole Didrik; Rolff, Hans Christian; Høyer Hansen, Gunilla; Vainer, B.; Osterlind, Kell; Illemann, Martin (2015-08-14)

Proteolytic activity and inflammation in the tumour microenvironment affects cancer progression. In colorectal cancer (CRC) liver metastases it has been observed that three different immune profiles are present, as well ...