Now showing items 1-10 of 31
Hallazgos fenotípicos por imágenes con Tomografía Dental Volumétrica (TDV) en amelogénesis imperfecta
Use of Dental Volumetric Tomography for Dental Phenotyping In Amelogenesis Imperfecta
Amelogénesis imperfecta (AI) se describe como un conjunto de defectos mendelianos en la biomineralización del esmalte dental, los cuales son severos en la mayoría de los casos al presentar anormalidades tales como un grosor ...
Neuropsychological Test Performance in Cognitively Normal Spanish-speaking Nonagenarians with Little Education
To find associations of age, sex, and education with neuropsychological test performance in cognitively normal Spanish-speaking Costa Rican nonagenarians with little education; to provide norms; and to compare their ...
Genetic analysis of the dry forest timber tree Sideroxylon capiri in Costa Rica using AFLP
Sideroxylon capiri (“Tempisque”) is a threatened and economically important timber species in the dry forest of Costa Rica. To assess the extent of the genetic diversity between and within populations of this species, 86 ...
The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy that preferentially affects children and adolescents. Over 50% of human T-ALLs possess activating mutations of Notch1. The clerodane ...
Mastering analytical challenges for the characterization of pentacyclic triterpene mono- and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC and hyphenation with APCI-QTOF-MS
Pentacyclic triterpene mono- and diesters have been isolated from Calendula officinalis flowers. GC–MS, APCI-Exactive Orbitrap HR-MS and NMR allowed to identify the triterpene skeleton in various samples (different triterpene ...
Discovery of Tricyclic Clerodane Diterpenes as Sarco/Endoplasmic Reticulum Ca2+-ATPase Inhibitors and Structure−Activity Relationships
Tricyclic clerodane diterpenes (TCDs) are natural compounds that often show potent cytotoxicity for cancer cells, but their mode of action remains elusive. A computationally based similarity search (CDRUG), combined with ...
A distinctive oral phenotype points to FAM20A mutations not identified by Sanger sequencing
Biallelic FAM20A mutations cause two conditions where Amelogenesis Imperfecta (AI) is the presenting feature: Amelogenesis Imperfecta and Gingival Fibromatosis Syndrome; and Enamel Renal Syndrome. A distinctive oral phenotype ...
Updated checklist and analysis of completeness of the marine fish fauna of Isla del Coco, Pacific of Costa Rica
Isla del Coco, Costa Rica, is one of the five groups of oceanic islands of the Eastern Tropical Pacific (ETP), and is considered one of the most diverse. Since the mid-19th century, it has been the target of a number of ...
Growth and hydrogen production of outdoor cultures of Synechocystis PCC 6803
Synechocystis sp. PCC 6803, a freshwater cyanobacterium, was cultivated outdoors in a 50 L tubular photobioreactor to study the acclimation of cells to solar light in cultures grown at different initial mean biomass ...
Euphausiids (Crustacea: Euphausiacea) from a hotspot of marine biodiversity, Isla del Coco, Costa Rica, Eastern Tropical Pacific
Eufáusidos (Crustacea: Euphausiacea) de un punto caliente de biodiversidad marina, Isla del Coco, Costa Rica, Pacífico Tropical Oriental
Euphausiids have been well studied in several regions of the Pacific Ocean; however, there is less information regarding euphausiids in Costa Rican waters. We analyzed euphausiid specimens collected around Isla del Coco ...