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Neutralization of proteolytic and hemorrhagic activities of Costa Rican snake venoms by a polyvalent antivenom
(1985)
The polyvalent antivenom produced at the Instituto Clodomiro Picado, Costa Rica, was tested for its capacity to neutralize proteolytic and hemorrhagic activities of ten Costa Rican crotaline venoms. In experiments with ...
Comparative study of the edema-forming activity of Costa Rican snake venoms and its neutralization by a polyvalent antivenom
(1986)
The edema-forming activity of eight Costa Rican crotaline snake venoms and its neutralization by a polyvalent antivenom were studied using the mouse footpad test. All of the venoms induced edema, the highest activity being ...
Karyotype of the yellow-bellied sea snake, Pelamis platurus
(1980)
In this paper we describe the karyotype of the yellow-bellied sea snake, Pelamis platurus from Costa Rica. The diploid number is 38 chromosomes, with 20 macrochromosomes and 18 microchromosomes. The pairs 1 and 2 are ...
Clodomiro Picado y sus años de formación científica
(1989)
Se analizan una serie de factores socioeconómicos, políticas y culturales que jugaron un papel importante en los años de formación del científica costarricense Clodomiro Picado Twight. E! desarrollo político y cultural de ...
Isolation of a myotoxin from Bothrops asper venom: Partial characterization and action on skeletal muscle
(1984)
A myotoxic phospholipase has been isolated from Bothrops asper venom by ion-exchange chromatography on CM-Sephadex followed by gel filtration on Sephadex G-75. The toxin is a basic polypeptide with an estimated molecular ...
Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco
(1980)
Pathogenesis of the myonecrotic, hemorrhagic and edema-forming effects in white mice inoculated with Bothrops asper venom was studied at different time intervals by means of light microscopy, determination of serum levels ...
Skeletal muscle regeneration after myonecrosis induced by crude venom and a myotoxin from the snake Bothrops asper (Fer-de-Lance).
(1984)
Skeletal muscle regeneration was studied following injections of Bothrops asper venom and a myotoxin isolated from the crude venom. In toxin-injected muscle regeneration proceeded normally. By 4 days there were myotubes ...
Mecanismo de acción de miotoxinas aisladas de venenos de serpientes
(1984)
Biochemically and pharmacologically, myotoxins isolated from snake venoms can be placed in four main groups: myolaxic phospholipases A, low molecular weight basic toxins, cardiotoxins, and hemorrhagic myotoxins. The myotoxic ...
Costa rican international cooperative biodiversity group: using insects and other arthropods in biodiversity prospecting
In: J. Rosenthal (Ed.). Drug discovery, economic development and conservation: The International Cooperative Biodiversity Groups. Pharm. Biol. Vol 37, Supplement, pp. 55-68.
(Pharmaceutical Biology 37(Supplement):55–68. 1999, 1999)
This paper describes the Costa Rican International Collaborative Biodiversity Group (ICBG), which was designed to introduce insects and other arthropods as a source of pharmaceutical compounds, and to generate knowledge ...
El problema de los efectos hemorrágico y mionecrótico por mordeduras de serpiente en el continente Americano
(1980)
Los efectos locales que aparecen como consecuencia de la mordedura de serpientes constituyen un problema de salud importante en las Américas. Sin embargo, la eficacia del suero antiofídico que se usa parece ser escasa, ...