Now showing items 1-10 of 22
Estudio comparativo de los venenos de serpiente Cascabel (Crotalus durissus durissus) de ejemplares adultos y recien nacidos
Comparative study of venoms of newborn and adult rattlesnakes (Crotalus durissus durissus)
Venoms from adult and newborn Central American rattlesnakes (Crotalus durissus durissus) were compared for lethal, proteolytic, hemorrhagic, myonecrotic, edematigenous and in vitro hemolytic activities. Electrophoretic and ...
Efectos proteolitico, hemorragico y mionecrotico de los venenos de serpientes costarricenses de los generos Bothrops, Crotalus y Lachesis
We studied the proteolytic, hemorrhagic and myonecrotic activities of ten Costa Rican species of snakes from the family Viperidae. All of them showed these three activities but we did not observe any correlation between ...
Estudios cariológicos de cinco especies de serpientes costarricenses de la familia colubridae
The karyotypes of five species of colubrid snakes from Costa Rica are as follows: Imuntodes cenchao and Drymobius margaritiferus have a diploid number of 36, with 16 macro- and 20 microchromosomes. The fourth pair is ...
Quantitation of myonecrosis induced by myotoxin a from prairie rattlesnake (Crotalus viridis viridis) venom
Using a pure myotoxin (myotoxin a) isolated from prairie rattlesnake Crotalus viridis viridis) venom, a comparison between two methods for quantitating myonecrosis in mice was made. Measurement of creatine kinase (CK) ...
Clodomiro Picado y sus años de formación científica
Se analizan una serie de factores socioeconómicos, políticas y culturales que jugaron un papel importante en los años de formación del científica costarricense Clodomiro Picado Twight. E! desarrollo político y cultural de ...
Costa rican international cooperative biodiversity group: using insects and other arthropods in biodiversity prospecting
In: J. Rosenthal (Ed.). Drug discovery, economic development and conservation: The International Cooperative Biodiversity Groups. Pharm. Biol. Vol 37, Supplement, pp. 55-68.
(Pharmaceutical Biology 37(Supplement):55–68. 1999, 1999)
This paper describes the Costa Rican International Collaborative Biodiversity Group (ICBG), which was designed to introduce insects and other arthropods as a source of pharmaceutical compounds, and to generate knowledge ...
Isolation of a myotoxin from Bothrops asper venom: Partial characterization and action on skeletal muscle
A myotoxic phospholipase has been isolated from Bothrops asper venom by ion-exchange chromatography on CM-Sephadex followed by gel filtration on Sephadex G-75. The toxin is a basic polypeptide with an estimated molecular ...
Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper
A toxic phospholipase A was isolated from the venom of Bothrops asper. It induced skeletal muscle damage, anticoagulant effects and edema in the foot pad. The toxin had an intravenous LD50 of 95 micrograms/16-18 g mouse ...
Mionecrosis, hemorragia y edema inducidos por el veneno de Bothrops asper en ratón blanco
Pathogenesis of the myonecrotic, hemorrhagic and edema-forming effects in white mice inoculated with Bothrops asper venom was studied at different time intervals by means of light microscopy, determination of serum levels ...
Pathogenesis of myonecrosis induced by crude venom and a myotoxin of Bothrops asper.
The pathogenesis of skeletal muscle necrosis induced by crude Bothrops asper venom and isolated myotoxic phospholipase was studied using light and electron microscopy. White mice were injected intramuscularly with a dose ...