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dc.creatorAngulo Ugalde, Yamileth
dc.creatorLomonte, Bruno
dc.date.accessioned2018-03-19T14:07:20Z
dc.date.available2018-03-19T14:07:20Z
dc.date.issued2009-12-01
dc.identifier.citationhttps://www.sciencedirect.com/science/article/pii/S0041010108006326es_ES
dc.identifier.issn0041-0101
dc.identifier.urihttp://hdl.handle.net/10669/74300
dc.description.abstractThe isolation and study of individual snake venom components paves the way for a deeper understanding of the pathophysiology of envenomings – thus potentially contributing to improved therapeutic modalities in the clinical setting – and also opens possibilities for the discovery of novel toxins that might be useful as tools for dissecting cellular and molecular processes of biomedical importance. This review provides a summary of the different toxins that have been isolated and characterized from the venom of Bothrops asper, the snake species causing the majority of human envenomings in Central America. This venom contains proteins belonging to at least eight families: metalloproteinase, serine proteinase, C-type lectin-like, L-amino acid oxidase, disintegrin, DC-fragment, cystein-rich secretory protein, and phospholipase A2. Some 25 venom proteins within these families have been isolated and characterized. Their main biochemical properties and toxic actions are described, including, in some cases, their possible relationships to the pathologic effects induced by B. asper venom.es_ES
dc.description.sponsorshipUniversidad de Costa Rica//UCR/Costa Ricaes_ES
dc.language.isoen_USes_ES
dc.sourceToxicon, vol. 54(7), pp.949-957es_ES
dc.subjectBothrops asperes_ES
dc.subjectToxines_ES
dc.subjectSnake venomes_ES
dc.titleBiochemistry and toxicology of toxins purified from the venom of the snake Bothrops asperes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.typeArtículo científicoes_ES
dc.identifier.doi10.1016/j.toxicon.2008.12.014
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)es_ES
dc.description.procedenceUCR::Vicerrectoría de Docencia::Salud::Facultad de Medicina::Escuela de Medicinaes_ES
dc.identifier.pmid19111755


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