Umbilical Cord Immunoglobulins and Fetal Maturity: Neonates in a Guatemalan Indian Village
Artículo científico

Date
1977Author
Mata Jiménez, Leonardo
Villatoro, Elba
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During a 9-year prospectivestudy in a Mayan Indian village (1), umbilical
cord blood was collected by untrained midwivesfrom most newborns. Specimens
mixed with maternal blood were screened according to their ratios of
immunoglobulinM (IgM) to immunoglobulinA (lgA) (2). All remaining
specimens with levels of IgA equal to or greater than 0.10 mg/rnl were also
excluded. Of the 401 original specimens, 250 were used in the study. Analysis of variance revealed no clear pattern associating IgM values with
birth weight or gestational age (Table 2,3). Highest values were noted in
infants of 35 to 36 weeks' gestation. Comparison of IgM values with combined
birth weight and gestational age (fetal maturity) showed that the
highest values were in three infants classifiedas pretenn, moderate low birthweight
(Table 4). Analysis of IgG values, on the other hand, revealed a
clear pattern; mean IgG was significantly correlated with birth weight, increasing
until birth weight reached 3,000 g. The correlation with gestational
age was even higher, lasting until 41-42 weeks' gestation. The lowest IgG
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