Synthesis and Evaluation of Aromatic Surfactants as Potential Antibacterial and Cytotoxic Agents
Barrantes Jiménez, Kenia
Chacón Jiménez, Luz María
Achí Araya, María Rosario
Vázquez Tato, José
Vázquez Tato, María del Pilar
Granados Zúñiga, Jorge
Alvarado, María José
Somarribas Patterson, Luis Felipe
Seijas, Julio A.
Soto Tellini, Victor Hugo
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Two ether and one ester derivatives of the 4-nitro-3-hydroxybenzoic acid were synthesized and characterized. The in vitro antimicrobial and cytotoxic activities of the three novel compounds were also evaluated. The aromatic derivatives showed antibacterial activity against one of the four microorganisms tested and two compounds (C8 and NOBA) had a lower IC50 in HeLa cells.
External link to the item10.2174/1570178615666181023151308
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