Show simple item record

dc.creatorCornelis, Marilyn C.
dc.creatorEl-Sohemy, Ahmed
dc.creatorKabagambe, Edmond K.
dc.creatorCampos Núñez, Hannia
dc.date.accessioned2021-05-18T21:03:59Z
dc.date.available2021-05-18T21:03:59Z
dc.date.issued2006
dc.identifier.citationhttps://jamanetwork.com/journals/jama/fullarticle/202502?resultClick=1es_ES
dc.identifier.issn1538-3598
dc.identifier.urihttps://hdl.handle.net/10669/83488
dc.description.abstractontext The association between coffee intake and risk of myocardial infarction (MI) remains controversial. Coffee is a major source of caffeine, which is metabolized by the polymorphic cytochrome P450 1A2 (CYP1A2) enzyme. Individuals who are homozygous for the CYP1A2*1A allele are “rapid” caffeine metabolizers, whereas carriers of the variant CYP1A2*1F are “slow” caffeine metabolizers. Objective To determine whether CYP1A2 genotype modifies the association between coffee consumption and risk of acute nonfatal MI. Design, Setting, and Participants Cases (n = 2014) with a first acute nonfatal MI and population-based controls (n = 2014) living in Costa Rica between 1994 and 2004, matched for age, sex, and area of residence, were genotyped by restriction fragment–length polymorphism polymerase chain reaction. A food frequency questionnaire was used to assess the intake of caffeinated coffee.es_ES
dc.language.isoenges_ES
dc.sourceJAMA. 2006; 295(10)es_ES
dc.subjectSaludes_ES
dc.subjectInfarto de miocardioes_ES
dc.subjectCafées_ES
dc.titleCoffee, CYP1A2 Genotype, and Risk of Myocardial Infarctiones_ES
dc.typeartículo científicoes_ES
dc.identifier.doi10.1001/jama.295.10.1135
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro Centroamericano de Población (CCP)es_ES


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record