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dc.creatorMadrigal Redondo, German
dc.creatorTromp, S.
dc.creatorMasís Alpízar, S.
dc.creatorChavarría Rojas, Marianela
dc.creatorSibaja Rodríguez, Santiago
dc.creatorAcuña Cubillo, C.
dc.date.accessioned2021-11-30T19:15:45Z
dc.date.available2021-11-30T19:15:45Z
dc.date.issued2019
dc.identifier.citationhttps://storage.googleapis.com/journal-uploads/ejbps/article_issue/volume_6_march_issue_3/1551775559.pdf
dc.identifier.issn2349-8870
dc.identifier.urihttps://hdl.handle.net/10669/85359
dc.description.abstractThe present study was carried out with the purpose of validating an analytical method for the quantification of the immediate release of tablets of chlorpheniramine maleate 4 mg and the determination or the dissolved percentage of them in three buffers, using a UV-Vis spectrophotometer for the analysis of these data. The analytical results show that the method complies with the parameters of linearity, precision and accuracy. The calibration curve of each medium was carried out in a concentration range of 2-14 μg / mL, linearity was demonstrated in each medium, considering the following criteria: homoscedasticity, variance analysis, correlation coefficient and random distribution data; precision was evaluated in terms of repeatability and intermediate precision; and finally, the accuracy was evaluated by the determination of recovery percentage. Therefore, the methodology complies with the specifications established by USP 40.es_ES
dc.language.isoenges_ES
dc.sourceEuropean Journal of Biomedical and Pharmaceutical sciences, vol.6(3), pp.118-134es_ES
dc.subjectChlorpheniramine maleatees_ES
dc.subjectPharmaceutical equivalencees_ES
dc.subjectValidationes_ES
dc.subjectAnalytical methodses_ES
dc.titleValidation of an analytical method for a comparative profiles of in vitro therapeutic equivalence of immediate release tablets of chlorpheniramine maleate 4 mges_ES
dc.typeartículo científico
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto de Investigaciones Farmacéuticas (INIFAR)es_ES


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