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dc.creatorZavala, Juan Manuel
dc.creatorDassori, Albana
dc.creatorEscamilla, Michael
dc.creatorRaventós Vorst, Henriette
dc.creatorNicolini Sánchez, José Humberto
dc.creatorOntiveros Sánchez de la Barquera, Jose Alfonso
dc.creatorJerez, Álvaro
dc.creatorContreras Rojas, Javier
dc.creatorRamírez, Mercedes
dc.creatorContreras, Salvador
dc.creatorFlores, Deborah
dc.creatorLeach, Robin J.
dc.creatorArmas, Regina
dc.creatorGonzález, S. D.
dc.date.accessioned2014-03-04T21:31:56Z
dc.date.available2014-03-04T21:31:56Z
dc.date.issued2013-05-28
dc.identifier.issn2158-3188
dc.identifier.otheressn: 2158-3188
dc.identifier.urihttp://hdl.handle.net/10669/9236
dc.descriptioncomunicación--Universidad de Costa Rica, Centro de Investigación en Biología Celular y Molecular, 2013es
dc.description.abstractSome of the most consistent findings have been in variants located in the ANK3 (ankyrin-G) gene located on chromosome 10q. Schultz et al.4 found that BP risk alleles in ANK3, rs9804190 and rs10994336, contributed independently to BP with no significant marker–marker interaction. we have designed a family-based association study to evaluate single-nucleotide polymorphisms (SNPs) spanning the ANK3 gene, including GWAS-significant SNPs rs9804190 and rs10994336, in 215 Latino pedigrees with reported ancestry from Mexico or Central America. All study participants were diagnosed using Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria using a best-estimation consensus procedure as previously described.7 Of the 929 individuals in this study, 466 were diagnosed with BPI and 16 were diagnosed with SABP.es
dc.description.sponsorshipUniversidad de Costa Ricaes
dc.language.isoen_USes
dc.publisherTranslational Psychiatry (2013) 3, e265es
dc.subjectGenéticaes
dc.subjectAmérica Latinaes
dc.subjectTranstorno Bipolares
dc.subjectAnkyrin-Ges
dc.titleFamily-based association of an ANK3 haplotype with bipolar disorder in Latino populationses
dc.typeinfo:eu-repo/semantics/otheres
dc.identifier.doi10.1038/tp.2013.40
dc.description.procedenceUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigación en Biología Celular y Molecular (CIBCM)es


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