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Hybrid mathematical modeling decodes the complexity of sphingolipid pathway to predict chemosensitivity
Sphingolipid (SL) signaling pathway is a complex biological system able to integrate different types of cellular stress signals related to induction of cell death pathways with special interest in cancer. This makes of ...
A hybrid mathematical modeling approach of the metabolic fate of a fluorescent sphingolipid analogue to predict cancer chemosensitivity
Sphingolipid (SL) metabolism is a complex biological system that produces and transforms ceramides and other molecules able to modulate other cellular processes, including survival or death pathways key to cell fate ...