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Leucemia Mieloide Crónica Juvenil. A propósito de un caso
Juvenile Chronic Myelogenous Leukemia. A Case Report
(2019-05-01)
La leucemia Mieloide Crónica (LMC) es una neoplasia mieloproliferativa crónica,
caracterizada por un gen de fusión t(9,22). El curso normal de la enfermedad consta de 3
fases: crónica, acelerada y blástica. En su gran ...
Programa de la evaluación externa de la calidad en coagulación sanguínea en Costa Rica utilizando plasma fresco congelado y de hematología básica con sangre estabilizada (PEEC- CIHATA-2020)
(2020-12-16)
Informe sobre la evolución del Programa de Evaluación Externa del CIHATA.
Repaso de conceptos y datos incluidos en el reporte.
Método para la producción de formulaciones inyectables de productos proteicos hemoderivados y productos obtenidos utilizando dicho método
(2011-04-08)
The invention relates to a method for producing injectable pharmaceutical formulations of blood-derived protein materials, including the steps of fractioning the source material in a polymer/salt aqueous two-phasesystem ...
Myotoxin-neutralizing peptides
PEPTIDES NEUTRALISANT LES MYOTOXINES
(2018-03-27)
The present invention relates to polypeptides having myotoxin-neutralizing properties and their use for treatment of envenomation. The present invention further relates to methods for neutralizing a venom using the polypeptide ...
Derived proteins from cry genes of bacillus thuringiensis
(2018-10-15)
Combinations of Bacillus thuringiensis (Bt) proteins and nucleic acids encoding these Bt proteins are disclosed. Plants transformed with nucleic acids encoding these Bt proteins are also disclosed
Venomics of the Central American Lyre snake Trimorphodon quadruplex (Colubridae: Smith, 1941) from Costa Rica
(2020)
Rear-fanged colubrid snakes include hundreds of species globally that possess a Duvernoy's venom gland and often one-several enlarged rear maxillary teeth. We investigated the venom proteome of the Central American Lyre ...
12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages
(2020)
The snake venom myotoxin (MT)-III is a group IIA secreted phospholipase A2 (sPLA2) with pro-inflammatory activities. Previous studies have demonstrated that MT-III has the ability to stimulate macrophages to release ...
Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential
(2020)
C. difficile induces antibiotic-associated diarrhea due to the action of two secreted toxins, TcdA and TcdB. A considerable range of virulence among C. difficile strains has been widely reported. During a hospital outbreak, ...
Venom diversity in the neotropical genus Tityus: implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism
(2020)
Scorpions of the Neotropical genus Tityus are responsible for most severe envenomations in the Caribbean, South America, and Lower Central America (LCA). Although Tityus is taxonomically complex, contains high toxin ...
Snake venomics, experimental toxic activities and clinical characteristics of human envenomation by Bothrocophias myersi (Serpentes: Viperidae) from Colombia
(2020)
Venoms of the viperid genus Bothrocophias, restricted to Colombia and Ecuador, are poorly known. Only a proteomic analysis of B. campbelli venom has been described. In this work we present a proteomic study of B. myersi ...