The genetic diversity of nine Amerindian tribes (Borne*, Bokota, Bribri, Cabecar, Gourmet, Guaymi., Hues's, Kuna and Teribe) from Costa Rica and Panama were analyzed using 48 loci of enzimatic systems, blood groups and ...

A screening of more than 40 loci was performed in the Bribri and Cabecar Amerindian populations of Talamanca in Southeastern Costa Rica. Some differences were found in the distribution (presence or absence) of the variants ...

Sparteine sulfate (50 mg) was administered to 170 Cuna Amerindians, 142 of whom were unrelated, and the drug and its dehydrometabolites were determined in the 0- to 12-hour urine samples. The log10 of the metabolic ratio ...

A biomedical study which included genetic, demographic, nutritional and health aspects was carried out in two amerindian Guayrni populations, Abrojo and Limoncito, located in Southeastern Costa Rica. Both groups originated ...

Carta al editor. Torroni et al. (1993) presented an extensive restriction-site analysis of Native American mtDNAs from 17 widely dis- tributed Na-Dene and Amerindian tribes. For sometime we have been analyzing mtDNA control ...

We have analysed genetic variation at 23 microsatellite loci in a global sample of 16 ethnically and geographically diverse human populations. On the basis of their ancestral heritage and geographic locations, the studied ...

A partir de 1979 se realizó un programa de investigación biomédica en varias poblaciones amerindias de Costa Rica que incluye estudios demográficos, ecológicos, genéticos, epidemiológicos y de salud. Los datos demográficos ...

Abstract. Charcot-Marie-Tooth disease type IB (CMT 1B) is caused by mutations in the gene coding for peripheral myelin protein zero (MPZ, P0) that plays a fundamental role in adhesion and compaction of peripheral myelin. ...

To better understand the evolutionary history of the gene region containing the multifunctional adipose tissue hormone leptin, we genotyped 1,957 individuals from 12 world populations for a highly variable tetranucleo ...

Definitions of genetic polymorphism currently employed in the pharmacological literature have been incorrectly used (Kalow, 1984) and uncritically imported from population genetics [e.g., Weinshilboum (1984), Evans (1977)], ...