2015-06-222015-06-222015-04-01http://revistas.ucr.ac.cr/index.php/clinica/article/view/18869https://hdl.handle.net/10669/14933Cryptogenic organizing pneumonia (COP) is a distinct histopathologic entity characterized byMasson bodies which are intraalveolar buds of granulation tissue; consisting of connective tissue and myofibroblasts. This pathologic pattern when present with the characteristic imaging and clinical features of COP defines the diagnosis of the disease. A specific etiology is not found. Treatment with corticosteroids results in a rapid clinical and imaging improvement but unfortunately relapses are common upon decreasing the dose or stopping the treatment. This case report describes a typical case of COP with the characteristic improvement with corticosteroid therapy and relapse upon treatment taperCryptogenic organizing pneumonia (COP) is a distinct histopathologic entity characterized by Masson bodies which are intraalveolar buds of granulation tissue; consisting of connective tissue and myofibroblasts. This pathologic pattern when present with the characteristic imaging and clinical features of COP defines the diagnosis of the disease. A specific etiology is not found. Treatment with corticosteroids results in a rapid clinical and imaging improvement but unfortunately relapses are common upon decreasing the dose or stopping the treatment. This case report describes a typical case of COP with the characteristic improvement with corticosteroid therapy and relapse upon treatment taperKEY-Cryptogenic organizing pneumoniaintraalveolar fibrosisbutterfly patternbronchiolitis obliterans organizing pneumoniaalveolar wallMasson bodiesartículo original2015-06-22es10.15517/rc_ucr-hsjd.v5i2.18869