A New Method for the Preparation of 1,5-Diynes. Synthesis of (4E,6Z,10Z)-4,6,10-Hexadecatrien-1-ol, the Pheromone Component of the Cocoa Pod Borer Moth Conopomorpha cramerella

Pereira, Albán R.; Cabezas Pizarro, Jorge A.

doi:https://doi.org/10.1021/jo048019y

A New Method for the Preparation of 1,5-Diynes. Synthesis of (4E,6Z,10Z)-4,6,10-Hexadecatrien-1-ol, the Pheromone Component of the Cocoa Pod Borer Moth Conopomorpha cramerella

Archivos

#18 Pereira-Cabezas JOC, 2005, 70, 2594.pdf (142,97 KB)

Fecha

2004

Authors

Pereira, Albán R.

Cabezas Pizarro, Jorge A.

DOI

https://doi.org/10.1021/jo048019y

Resumen

A new method for the synthesis of 1,5-diynes, from the reaction of 1,3-dilithiopropyne and propargyl chlorides, was developed. This new methodology was used to prepare (4E,6Z,10Z)-4,6,10-hexadecatrien-1-ol, one of the pheromone components of the cocoa pod borer moth Conopomorpha cramerella, in 51% overall yield.